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Nef Mediated CD4 Down-Regulation

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-167590).

Statements about Nef Mediated CD4 Down-Regulation

Instance Of

Biological Pathway
Mitigation of Host Defenses by Virus

Part Of

Nef-Mediates Down Modulation of Cell Surface Receptors by Recruiting Them to Clathrin Adapters

Has Part(s)

Nef Mediated Disruption of CD4:Lck Complex
Formation of CD4:Nef:AP-2 Complex:v-ATPase Complex
Internalization of the CD4:Nef:AP-2 Complex:v-ATPase Complex
Formation of a Nef:ARF1:CD4 Complex
Degradation of CD4

Exact Match

https://identifiers.org/reactome:R-H ...
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