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Nef and Signal Transduction - Ontify

Nef and Signal Transduction

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-164944).

Statements about Nef and Signal Transduction

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Instance Of

Biological Pathway

Mitigation of Host Defenses by Virus

Part Of

The Role of Nef in HIV-1 Replication and Disease Pathogenesis

Has Part(s)

Nef Mediated Activation of the T-Cell Receptor

Nef Binds and Activates the Src-Family Tyrosine Kinase Hck

Nef Binds and Activates the Src-Family Tyrosine Kinase Fyn

Nef Binds and Activates the Src-Family Tyrosine Kinase Lck

Nef Binds a Ternary Complex Comprising DOCK2 Guanine Nucleotide Exchange Factor for Small Rho-Family GTPase Rac, Its Cofactor ELMO1, and Rac, and Activates Rac Through This Interaction

Exact Match

https://identifiers.org/reactome:R-H ...