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Binding and Entry of HIV Virion - Ontify

Binding and Entry of HIV Virion

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-173107).

Statements about Binding and Entry of HIV Virion

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Instance Of

Biological Pathway

Entry Into Host

Part Of

Early Phase of HIV Life Cycle

Has Part(s)

Binding of Gp120 of ENV Oligomer to the Host CD4

Conformational Change in Gp120 of Env Oligomer

CD4:gp120 Binds to Chemokine Co-Receptor CCR5/CXCR4

Conformational Changes in Gp120 Exposes Gp41

Fusogenic Activation of Gp41

Insertion of Gp41 Fusion Peptide Into the Target Membrane

N and C Terminal Heptad Repeat Helices of Gp41 Form Six-Helix Bundle

Fusion of Viral Membrane with Host Cell Membrane

Exact Match

https://identifiers.org/reactome:R-H ...