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Signaling by High-Kinase Activity BRAF Mutants - Ontify
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Signaling by High-Kinase Activity BRAF Mutants
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-6802948).
Statements about
Signaling by High-Kinase Activity BRAF Mutants
Instance Of
Biological Pathway
Part Of
Oncogenic MAPK Signaling
Has Part(s)
High Kinase Activity BRAF Mutants Bind MAP2Ks and MAPKs
Exact Match
https://identifiers.org/reactome:R-H ...
Inhibitors Bind and Inhibit Highly Active BRAF Mutants
Dissociation of High Activity BRAF Complexes
High Kinase Activity BRAF Complexes Phosphorylate MAP2Ks
Activated MAP2Ks Phosphorylate MAPKs Downstream of High Kinase Activity BRAF Mutants
Dimerization of BRAF V600E Splice Variants Contributes to BRAF Inhibitor Resistance
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