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Formation of the Cornified Envelope
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-6809371).
Statements about
Formation of the Cornified Envelope
Instance Of
Biological Pathway
Cornification
Part Of
Keratinization
Has Part(s)
27 items
Envoplakin Binds Periplakin
Envoplakin, Periplakin, Involucrin, SPR Binding Mediated by TGM1 Crosslinking
TGM1 and Involucrin Bind the Plasma Membrane
EVL:PPL Heterodimer Binds the Inner Surface of the Plasma Membrane
Membrane Proteases Cleave Profilaggrin Producing Filaggrin
Cytoplasmic Proteases Cleave Profilaggrin Producing Filaggrin
Filaggrin Binds Keratin Tonofilament:Desmosome
Fillagrin and Keratin Intermediate Filaments Polymerise Forming a Network
Lamellar Bodies Bind the Early Cornified Envelope
Reinforcement of the Cornified Envelope
CDSN Binds the Cornified Envelope
Late Envelope Proteins Bind Cornified Envelope:CDSN
Kazrin Binds Periplakin
CASP14 Cleaves Filaggrin
PERP Binds Desmosomes
Plasma Membrane Resorption
ST14 Hydrolyzes and Activates KLK5
SPINK5(490-624) Binds KLK5
Dissociation of the SPINK5:KLK5 Complex at Low pH
KLK5 Cleaves and Activates CELA2
KLK5 Cleaves and Activates KLK8
SPINK6 Binds KLK12
SPINK6 Binds KLK13
SPINK6 Binds KLK14
LIPs Hydrolyse TG to DAG and RCOOH
SPINK6 Binds KLK5
SPINK9 Binds KLK5
Exact Match
https://identifiers.org/reactome:R-H ...
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