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Signaling by NODAL
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-1181150).
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Signaling by NODAL
Instance Of
Biological Pathway
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Has Part(s)
10 items
Exact Match
https://identifiers.org/reactome:R-H ...
Regulation of Signaling by NODAL
The NODAL Receptor Binds NODAL Ligands
Developmental Biology
Phospho R-SMAD(SMAD2,3):CO-SMAD(SMAD4):FOXH1 Binds Activin Response Element
Phosphorylated SMAD2 and SMAD3 Form a Complex with SMAD4
Cleavage of NODAL Proprotein
Type II Activin Receptor (ActRIIB/ACVR2B) Phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in Response to NODAL
Type II Activin Receptor (ActRII/ACVR2) Phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in Response to NODAL
The SMAD2/3:SMAD4 Complex Transfers to the Nucleus
Phosphorylation of R-SMAD2/3 by NODAL Receptor
Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 Binds FoxO3a-Binding Elements