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RET Signaling
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-8853659).
Statements about
RET Signaling
Instance Of
Biological Pathway
Part Of
Axon Guidance
Has Part(s)
24 items
P-5Y-GAB in the RET-GRB2-GAB Complexes Binds P85-PI3K
Exact Match
https://identifiers.org/reactome:R-H ...
RET Binds GFRA1,GFRA3
RET Binds GFRA1,GFRA2
RET Tyrosine Phosphorylation
PSPN Binds RET:GFRA4
2x P-5Y-RET:GDNF:GFRA Complexes:p-Y349,Y350,Y427-SHC1 Binds GRB2-1:SOS1
ARTN Binds RET:GFRA1,GFRA3
2x P-5Y-RET:GDNF:GFRA Complexes Bind GRB2-1:SOS1
2x P-5Y-RET:GDNF:GFRA Complexes Bind FRS2
RET Dimerizes
P-5Y-RET-GRB2-Containing Complexes Bind GAB1,GAB2
2x P-5Y-RET:GDNF:GFRA Complexes Binds DOK1,DOK2,DOK4,DOK5,DOK6
2x P-5Y-RET:GDNF:GFRA Complexes Bind PLCgamma1
GDNF,NRTN Bind RET:GFRA1,GFRA2
2x P-5Y-RET:GDNF:GFRA Complexes Bind RET Interactors
SHC1 in the RET Complex Is Phosphorylated
2x P-5Y-RET:GDNF:GFRA Complexes Bind SHC1
PKA Phosphorylates RET:GDNF:GFRA Dimer
2x P-5Y-RET:GDNF:GFRA Complexes Bind GRB7,10
GAB in P-5Y-RET:GDNF:GFRA Complexes Is Phosphorylated
2x P-5Y-RET:GDNF:GFRA Complexes Bind SRC1, RAP1GAP
RET Binds GFRA4
P-5Y-RET Complexes Bind GRB2
P-5Y-GAB in RET-GRB2-GAB Complexes Binds PTPN11
