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EPHB-Mediated Forward Signaling - Ontify
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EPHB-Mediated Forward Signaling
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-3928662).
Statements about
EPHB-Mediated Forward Signaling
Instance Of
Biological Pathway
Part Of
EPH-Ephrin Signaling
Has Part(s)
26 items
CDC42 and PIP2 Bind WASL, Activating It
ITSN1 Exchanges GTP for GDP on CDC42, Activating It
PAK1 Binds RAC1:GTP
RHOA:GTP Binds ROCK, Activating It
ROCK Phosphorylates LIMK1,2
FYN Phosphorylates NMDAR2B
EPHBs Bind NMDARs
EPHB:NMDAR Binds TIAM1
EPHB Phosphorylates TIAM1
P-TIAM1 Exchanges GTP for GDP on RAC1, Activating It
Exact Match
https://identifiers.org/reactome:R-H ...
N-WASP Binds ITSN1
EPHB Binds ITSN1
N-WASP Binds ARP2/3 and G-Actin
Recruitment of p190RhoGEF to P-FAK
EPHBs Binds PTK2
P-EPHB Phosphorylates SDC2
P190RhoGEF Exchanges GTP for GDP on RHOA, Activating It
SDC2 Multimerises
PAK1 Autophosphorylates
KALRN Exchanges GTP for GDP on RAC1, Activating It
LIMK Phosphorylates CFL1, Inactivating It
EPHB2 Binds KALRN
P120-RasGAP Activates GTP Hydrolysis on RAS, Inactivating It
EPHB Binds P120-RasGAP
PTK2 Autophosphorylates at Y397
Ras:GTP Binds P120-RasGAP
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