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Regulation of Expression of SLITs and ROBOs - Ontify
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Regulation of Expression of SLITs and ROBOs
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9010553).
Statements about
Regulation of Expression of SLITs and ROBOs
Instance Of
Biological Pathway
Part Of
Signaling by ROBO Receptors
Has Part(s)
20 items
SLIT2 Gene Expression Is Stimulated by ISL1
ISL1 Binds the SLIT2 Gene Enhancer
SLIT2 Binds Dystroglycan
SLIT1 Binds COL4A5
USP33 Deubiquitinates ROBO1
HOXA2 Binds ROBO2 Gene Promoter
LHX2 Binds to ROBO1 Gene Locus
ROBO1 Gene Expression Is Inhibited by LHX2
LHX2 Binds to ROBO2 Gene Locus
ROBO2 Gene Transcription Is Stimulated by HOXA2 and Inhibited by LHX2
ROBO3.1 Expression Is Stimulated by LHX2,(LHX9)
LHX2,(LHX9) Binds the ROBO3 Gene Promoter
MSI1 Binds ROBO3.1 mRNA
ROBO3.1 mRNA Translation Is Positively Regulated by MSI1
ZSWIM8 Binds ROBO3.1
ZSWIM8 Ubiquitinates ROBO3.1
Proteasome Degrades Ubiquitinated ROBO3.1
Transcription of ROBO3.2 mRNA
Translation of ROBO3.2 mRNA Initiates NMD
Translation of ROBO3.2 mRNA Is Negatively Regulated by NMD
Exact Match
https://identifiers.org/reactome:R-H ...
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