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Sensing of DNA Double Strand Breaks - Ontify

Sensing of DNA Double Strand Breaks

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5693548).

Statements about Sensing of DNA Double Strand Breaks

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Instance Of

Biological Pathway

Part Of

DNA Double Strand Break Response

Has Part(s)

DSB Inducing Agents Induce Double Strand DNA Breaks

MRN Complex Binds DNA Double Strand Breaks

KAT5 Acetylates ATM at DNA DSBs

MRN Activates ATM

MRN Complex Bound to DNA Ends Recruits ATM

Formation of RAD50:MRE11 Complex

NBN Binds KPNA2

KPNA2 Translocates NBN to the Nucleus

Association of RAD50:MRE11A Complex with NBN (NBS1) via MRE11A Interaction

Exact Match

https://identifiers.org/reactome:R-H ...