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Recognition of DNA Damage by PCNA-Containing Replication Complex - Ontify
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Recognition of DNA Damage by PCNA-Containing Replication Complex
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-110314).
Statements about
Recognition of DNA Damage by PCNA-Containing Replication Complex
Instance Of
Biological Pathway
Part Of
DNA Damage Bypass
Has Part(s)
Damaged dsDNA Becomes Damaged DNA Template
PCNA-Containing Replication Complex Binds Damaged dsDNA
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL Monoubiquitinates PCNA
USP1:WDR48 Binds monoUb:K164-PCNA
USP1:WDR48 Deubiquitinates monoUb:K164-PCNA
USP1 Autocleavage
Exact Match
https://identifiers.org/reactome:R-H ...
Positive Regulation of Error-Prone Translesion Synthesis
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL Ubiquitin Ligase Complex Binds PCNA:POLD,POLE:RPA:RFC Associated with Damaged dsDNA
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