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Meiotic Recombination - Ontify

Meiotic Recombination

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-912446).

Statements about Meiotic Recombination

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Instance Of

Biological Pathway

Part Of

Has Part(s)

PRDM9 Trimethylates Histone H3

PRDM9 Binds Recombination Hotspot Motifs in DNA

SPO11 Hydrolyzes DNA Forming Double-Strand Breaks

Formation of Meiotic Single-Stranded DNA Invasion Complex

Formation of Meiotic Heteroduplex

Formation of Meiotic Holliday Junction

Resolution of Meiotic Holliday Junction

MRN:CtIP Endonucleolytically Cleaves Single-Strand DNA 3' To SPO11

MRN:CtIP Exonucleolytically Hydrolyzes DNA 3' To SPO11 and SPO11:double-Strand Break Dissociates to SPO11:oligonucleotide and Resected 5' End

Exact Match

https://identifiers.org/reactome:R-H ...