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NOTCH1 HD+PEST Domain Mutants Are Cleaved by ADAM10/17 Irrespective of Ligand Binding - Ontify
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NOTCH1 HD+PEST Domain Mutants Are Cleaved by ADAM10/17 Irrespective of Ligand Binding
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2220976).
Statements about
NOTCH1 HD+PEST Domain Mutants Are Cleaved by ADAM10/17 Irrespective of Ligand Binding
Instance Of
Biological Process
Part Of
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
NOTCH1 HD+PEST Domain Mutants/Ub-DLL/JAG:NOTCH1 HD+PEST Domain Mutants [Plasma Membrane]
NEXT1 PEST Domain Mutants [Plasma Membrane]
NOTCH1 HD+PEST Domain Mutant Fragments/Ub-DLL/JAG:NOTCH1 HD+PEST Domain Mutant Fragments [Plasma Membrane]
ADAM10/17:Zn2+ [Plasma Membrane]
Object of Statement Has Role
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Reactant
Unnamed
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1
Object of Statement Has Role
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Product
Unnamed
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1
Object of Statement Has Role
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Product
Unnamed
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1
Object of Statement Has Role
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Modifier
Unnamed
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1
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