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Constitutive Signaling by NOTCH1 HD Domain Mutants - Ontify

Constitutive Signaling by NOTCH1 HD Domain Mutants

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2691232).

Statements about Constitutive Signaling by NOTCH1 HD Domain Mutants

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Instance Of

Biological Pathway

Part Of

Signaling by NOTCH1 HD Domain Mutants in Cancer

Has Part(s)

NOTCH1 HD Domain Mutants Bind DLL1

NOTCH1 HD Domain Mutants Bind DLL4

NOTCH1 HD Domain Mutants Bind JAG1

NOTCH1 HD Domain Mutants Bind JAG2

Ubiquitination of DLL/JAG Ligands upon Binding to NOTCH1 HD Domain Mutants

NOTCH1 HD Domain Mutants Are Cleaved to Produce NEXT1 Irrespective of Ligand Binding

Exact Match

https://identifiers.org/reactome:R-H ...