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Activation of ATR in Response to Replication Stress - Ontify

Activation of ATR in Response to Replication Stress

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-176187).

Statements about Activation of ATR in Response to Replication Stress

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Part Of

G2/M Checkpoints

Has Part(s)

Phosphorylation of Cdc25A at Ser-123 by Chk1

Recruitment and Activation of Chk1

Stalling of DNA Replication Fork and RPA Binding

Binding of ATR-ATRIP to the RPA-ssDNA Complex

Recruitment of Rad17-RFC Complex to DNA

Recruitment of the Rad9-Hus1-Rad1 Complex to DNA

Loading of Claspin Onto DNA During Replication Origin Firing

Activation of Claspin

Phosphorylation of Cdc25C at Ser 216 by Chk1

Instance Of

Biological Pathway

DNA Replication

Exact Match

https://identifiers.org/reactome:R-H ...