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Aspirin ADME

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9749641).

Statements about Aspirin ADME

Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Pathway

Xenobiotic Metabolic Process

Has Part(s)

26 items

UGTs Transfer GlcA From UDP-GlcA to O-Centre Substrates

CES1,CES2 Hydrolyze ASA- to ST

SLC16A1:BSG Cotransports Monocarboxylates, H+ From Extracellular Region to Cytosol

Part Of

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Hydroxyl Radicals Oxidize ST to 2,3-DHBA

ASA- Acetylates ALB

Acetylsalicylic Acid Dissolves

ASA- (GI) Translocates From Cytosol to Extracellular Region

ST Translocates From ER Lumen to Cytosol of GI Cells

SLC22A7 Transports ASA-,ST From Extracellular Region to Cytosol of Hepatocytes

Glycine Conjugates Translocates From Mitochondrial Matrix to Cytosol

ACSM2B-Like Proteins Transform 2,5-DHBA to 2,5-DHB-CoA

ST Translocates From Cytosol to Extracellular Region

UGT1A6 Glucuronates ST

ASA- Translocates From Cytosol to ER Lumen of GI Cells

ST Metabolites Diffuse Out of ER Lumen

SLCO2B1-1 Transports ASA- From Extracellular Region to Cytosol of GI Cells

CYP2,3 Cytochromes Hydroxylate ST to 2,3-DHBA

CYP2,3 Cytochromes Hydroxylate ST to 2,5-DHBA

BCHE Hydrolyzes ASA-

2,5-DHBA Translocates From ER Lumen to Mitochondrial Matrix

ABCC2, ABCC3 Transport Salicylate Metabolites From Cytosol to Extracellular Region of Hepatic Cells

GLYAT-Like Proteins Transfer Glycine to 2,5-DHB-CoA to Form Gentisuric Acid

ASA-,ST Translocate From Cytosol to ER Lumen of Hepatocytes

ST Translocates From Cytosol to Mitochondrial Matrix of Hepatocytes

CES2 Hydrolyzes ASA-