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Signaling by ALK Fusions and Activated Point Mutants

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9725370).

Statements about Signaling by ALK Fusions and Activated Point Mutants

Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Pathway

Has Part(s)

21 items
ALK Mutants Bind STAT3
ALK Mutants Bind PI3KR1
ALK Mutants:p-3Y SHC Binds GRB2
ALK Fusions Bind GRB2
ALK Mutants Phosphorylate SHC1
ALK Fusion Proteins Bind PLCG1
Nuclear Events Stimulated by ALK Signaling in Cancer
Autophosphorylation of Point Mutants of ALK
MYH9- and RNF213-ALK Fusions Are Phosphorylated
ALK Fusion Proteins Bind IRS
Ligand-Independent Dimerization of Point Mutants of ALK
ALK Mutants Bind SHC
ALK Mutants Bind PI3KCA
Ligand-Independent Dimerization of ALK Fusions
ALK Fusions Phosphorylate IRS1
ALK Fusions Bind FRS
ALK Fusions Phosphorylate FRS
ALK Fusions Phosphorylate PLCG1
ALK Mutants Phosphorylate STAT3
Autophosphorylation of ALK Fusions
PI3K Synthesizes PIP3 Downstream of ALK Mutants

Part Of

Signaling by ALK in Cancer
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