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BRCA2 Mutants with BRC Defects or a Defect in the C-Terminal RAD51 Binding Site Do Not Bind RAD51

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9709571).

Statements about BRCA2 Mutants with BRC Defects or a Defect in the C-Terminal RAD51 Binding Site Do Not Bind RAD51

Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Process

Has Part(s)

Part Of

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ATR:ATRIP:p-RPA:3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
P-T309-RAD51 [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
Impaired BRCA2 Binding to RAD51
BRCA2 Mutants (RAD51 Binding):SEM1 [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
: 1