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Defective Recruitment of BRCA2 and RAD51 Due to Loss of BRCA2 Function in PALB2 Binding - Ontify

Defective Recruitment of BRCA2 and RAD51 Due to Loss of BRCA2 Function in PALB2 Binding

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9709601).

Statements about Defective Recruitment of BRCA2 and RAD51 Due to Loss of BRCA2 Function in PALB2 Binding

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Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Process

Has Part(s)

3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:BRCA2 Mutants (PALB2 Binding):SEM1:BCDX2 Complex [Nucleoplasm]

Partner and Localizer of BRCA2

RAD51 Associated Protein 1

Part Of

Impaired BRCA2 Binding to PALB2

Object of Statement Has Role

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: 1

Object of Statement Has Role

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: 1

Object of Statement Has Role

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: 1