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Defective D-Loop Formation Mediated by PALB2, BRCA2 and RAD51 Due to Loss-of-Function of BRCA1 in PALB2 Binding - Ontify
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Defective D-Loop Formation Mediated by PALB2, BRCA2 and RAD51 Due to Loss-of-Function of BRCA1 in PALB2 Binding
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9701199).
Statements about
Defective D-Loop Formation Mediated by PALB2, BRCA2 and RAD51 Due to Loss-of-Function of BRCA1 in PALB2 Binding
Exact Match
https://identifiers.org/reactome:R-H ...
Instance Of
Biological Process
Has Part(s)
Defective 3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:BCDX2 Complex [Nucleoplasm]
Partner and Localizer of BRCA2
RAD51 Associated Protein 1
Part Of
Defective HDR Through Homologous Recombination (HRR) Due to BRCA1 Loss-of-Function
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Object of Statement Has Role
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Object of Statement Has Role
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