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PI3K-Binding ALK Mutants [Cytosol] - Ontify

PI3K-Binding ALK Mutants [Cytosol]

Instance of candidate set in Homo sapiens with Reactome ID (R-HSA-9711929).

Statements about PI3K-Binding ALK Mutants [Cytosol]

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Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Has Part(s)

22 items

P-7Y ALK F1174I Dimer [Plasma Membrane]

P-7Y ALK F1174L Dimer [Plasma Membrane]

P-7Y ALK I1171N Dimer [Plasma Membrane]

NPM1(1-117)-P-7Y ALK(1058-1620) Fusion Dimer [Cytosol]

P-7Y ALK G1128A Dimer [Plasma Membrane]

FN1(32-1201)-P-7Y ALK(1022-1620) Fusion Dimer [Plasma Membrane]

P-7Y ALK F1245C Dimer [Plasma Membrane]

P-7Y ALK R1192P Dimer [Plasma Membrane]

P-7Y ALK L1198F Dimer [Plasma Membrane]

P-7Y ALK Del318-782 Dimer [Plasma Membrane]

P-7Y ALK K1062M Dimer [Plasma Membrane]

P-7Y ALK G1201E Dimer [Plasma Membrane]

P-7Y ALK R1275Q Dimer [Plasma Membrane]

P-7Y ALK Del224-318 Dimer [Plasma Membrane]

Part Of

ALK Mutants Bind PI3KR1

: 1

: 1

: 1

: 1

: 1

: 1

: 1

: 1

: 1

: 1

: 1

: 1

: 1

: 1

KIF5B(2-575)-P-7Y ALK(1063-1620) Fusion Dimer [Cytosol]

: 1

EML4(1-223)-P-7Y ALK(1059-1620) Fusion Dimer [Cytosol]

: 1

P-7Y ALK F1174S Dimer [Plasma Membrane]

: 1

EML4(1-569)-P-7Y ALK(1078-1620) Fusion Dimer [Cytosol]

: 1

CLTC(2-1634)-P-7Y ALK(1059-1620) Fusion Dimer [Cytosol]

: 1

ALK Mutants:PIK3R1 [Cytosol]

EML4(1-486)-P-7Y ALK(1058-1620) Fusion Dimer [Cytosol]

: 1

EML4(1-223)insKMSTREKNSQV -P-7Y ALK(1059-1620) Fusion Dimer [Cytosol]

: 1

DCTN1(1-1065)-P-7Y ALK(1058-1620) Fusion Dimer [Cytosol]

: 1