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CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [Plasma Membrane] - Ontify

CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [Plasma Membrane]

Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-9676067).

Statements about CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [Plasma Membrane]

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Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Protein Complex

Has Part(s)

CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 [Plasma Membrane]

P-HCK [Cytosol]

P-JAK2 [Cytosol]

P-TYK2 [Cytosol]

P-Y-SYK [Cytosol]

Part Of

SOCS1,3:p-4Y-CSF3R:CSF3dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [Plasma Membrane]

CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-SHC1:GRB2:p-Y643-GAB2:p-Y546,Y584-PTPN11 [Plasma Membrane]

CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 Binds STAT1,3,5

CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 [Plasma Membrane]

SOCS1,3 Binds P-4Y-CSF3R:CSF3 Dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2

CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 Binds and Phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2)

CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:STAT1,3,5 [Plasma Membrane]

CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 Dissociates Yielding CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 and P-Y-STAT1,3,5

CSF3 Dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 Binds and Activates JAK2, TYK2, SYK, and HCK

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