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TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis - Ontify

TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9694661).

Statements about TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis

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Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Process

Has Part(s)

S3:M:E:encapsidated SARS-CoV-2 Genomic RNA: 7a:O-Glycosyl 3a Tetramer:glycosylated-ACE2:HSPGs [Extracellular Region]

Angiotensin I Converting Enzyme 2

HSPGs [Plasma Membrane]

Part Of

Attachment and Entry

Object of Statement Has Role

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Object of Statement Has Role

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Object of Statement Has Role

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Object of Statement Has Role

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S1:S2:M:E:encapsidated SARS-CoV-2 Genomic RNA: 7a:O-Glycosyl 3a Tetramer [Endocytic Vesicle Lumen]

Object of Statement Has Role

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TMPRSS2:TMPRSS2 Inhibitors [Plasma Membrane]

Object of Statement Has Role

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Transmembrane Serine Protease 2

Object of Statement Has Role

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Hepatitis A Virus Cellular Receptor 1

Object of Statement Has Role

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