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Extra-Nuclear Estrogen Signaling - Ontify

Extra-Nuclear Estrogen Signaling

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9009391).

Statements about Extra-Nuclear Estrogen Signaling

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Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Pathway

Has Part(s)

23 items

PRMT1 Methylates ESRs

ZDHHC7, ZDHHC21 Palmitoylate ESR1

PalmS-ESRs Bind CAVs

PalmS-ESRs:CAVs Translocate to Plasma Membrane

Estrogen Stimulates Dimerization of Plasma Membrane Estrogen Receptors

ESTG Binding Induces ESR Depalmitoylation

Heterotrimeric G Protein (I) Binds Membrane-Associated ESRs:ESTG

G-Proteins Dissociate From Plasma-Membrane Estrogen Receptors

Membrane Estrogen Receptors Bind SRC

ESR-Associated SRC Autophosphorylates

PI3K Binds Membrane-Associated Estrogen Receptors

ENOS Synthesizes NO

PTK2 Is Recruited to Methylated ESR1

Estrogen-Stimulated Signaling Through PRKCZ

Estrogen Receptor Binds IGF1R and SHC1 in Response to Estrogen

MMPs Cleave HB-EGF

PTK2 Binds Activated EGFR

PTK2 Autophosphorylates Downstream of EGFR

Estrogen-Dependent Nuclear Events Downstream of ESR-Membrane Signaling

SPHK1 Phosphorylates Sphingosine in Response to E2 Stimulation

S1P Binds S1PR3 in Response to E2 Stimulation

HSBP1 Oligomer Binds ESRs

Part Of

ESR-Mediated Signaling