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RAS Processing - Ontify
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RAS Processing
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9648002).
Statements about
RAS Processing
Exact Match
https://identifiers.org/reactome:R-H ...
Instance Of
Biological Pathway
Has Part(s)
21 items
Pro-RAS Proteins Are Farnesylated
FNTB Inhibitors Bind FNTA:FNTB
RCE1 Cleaves S-Farn proRAS Proteins
USP17L2 Deubiquitinates RCE1
ICMT Methylates S-Farn RAS Proteins
Cysmethynil Binds ICMT:Zn2+
S-Farn Me-HRAS, -NRAS and -KRAS4A Are Palmitoylated
Mature RAS Proteins Translocate to Plasma Membrane
RAS Proteins Are Depalmitoylated
Palmostatin B Binds RAS Depalmitoylases
Mature S-Farn-Me KRAS4B Translocates to Plasma Membrane
Mature P21 RAS Binds GDP
KRAS4B Is Phosphorylated on Serine 181
PS181-S-Farn-Me KRAS4B Translocates to the Outer Mitochondrial Membrane
PS181-S-Farn-Me KRAS4B Binds BCL2L1
S-Farn-Me KRAS4B Binds Calmodulin
Calmodulin Dissociates KRAS4B From the Plasma Membrane
PDE6D Binds S-Farn-Me KRAS4B:CALM:4 Ca2+
Deltarasin Binds PDE6D
ARL2:GTP Bind PDE6D on KRAS4B
KRAS4B Recycles to the Plasma Membrane
Part Of
RAF/MAP Kinase Cascade
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