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Defective Factor VIII Causes Hemophilia A - Ontify
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Defective Factor VIII Causes Hemophilia A
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9662001).
Statements about
Defective Factor VIII Causes Hemophilia A
Exact Match
https://identifiers.org/reactome:R-H ...
Instance Of
Biological Pathway
Has Part(s)
Defective F8 Sulfation at Y1699
Defective Cofactor Function of FVIIIa Variant
Part Of
Defects of Contact Activation System (CAS) and Kallikrein/Kinin System (KKS)
Defective F8 Secretion
Defective F8 Cleavage by Thrombin
Defective F8 Accelerates Dissociation of the A2 Domain
Defective F8 Binding to Von Willebrand Factor
Defective F8 Binding to the Cell Membrane