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Replication of the SARS-CoV-1 Genome
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9682706).
Statements about
Replication of the SARS-CoV-1 Genome
Exact Match
https://identifiers.org/reactome:R-H ...
Instance Of
Biological Pathway
Has Part(s)
21 items
Part Of
SARS-CoV-1 Genome Replication and Transcription
SARS Coronavirus gRNA:RTC:RNA Primer Binds RTC Inhibitors
Nsp12 Misincorporates a Nucleotide in Nascent RNA Minus Strand
Nsp14 Acts as a 3'-to-5' Exonuclease to Remove Misincorporated Nucleotides From Nascent RNA
Nsp8 Generates RNA Primers
RTC Completes Synthesis of the Minus Strand Genomic RNA Complement
Nsp13 Binds DDX5
Nsp16 Binds VHL
Nsp16 Acts as a Cap 2'-O-Methyltransferase to Modify SARS-CoV-1 gRNA (Plus Strand)
Nsp14 Acts as a Cap N7 Methyltransferase to Modify SARS-CoV-1 gRNA Complement (Minus Strand)
RTC Synthesizes SARS-CoV-1 Plus Strand Genomic RNA
Nsp15 Binds RB1
Nsp12 Synthesizes Minus Strand SARS-CoV-1 Genomic RNA Complement
Replication Transcription Complex Binds SARS-CoV-1 Genomic RNA
ZCRB1 Binds 5'UTR of SARS-CoV-1 Genomic RNA
SARS-CoV-1 gRNA:RTC:nascent RNA Minus Strand Binds RTC Inhibitors
Nsp13 Helicase Melts Secondary Structures in SARS-CoV-1 Genomic RNA Template
Nsp14 Acts as a Cap N7 Methyltransferase to Modify SARS-CoV-1 gRNA (Plus Strand)
RTC Binds SARS-CoV-1 Genomic RNA Complement (Minus Strand)
Polyadenylation of SARS-CoV-1 Genomic RNA (Plus Strand)
SARS-CoV-1 gRNA Complement (Minus Strand):RTC Binds RTC Inhibitors
Nsp16 Acts as a Cap 2'-O-Methyltransferase to Modify SARS-CoV-1 gRNA Complement (Minus Strand)