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Signaling by Phosphorylated Juxtamembrane, Extracellular and Kinase Domain KIT Mutants - Ontify

Signaling by Phosphorylated Juxtamembrane, Extracellular and Kinase Domain KIT Mutants

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9670439).

Statements about Signaling by Phosphorylated Juxtamembrane, Extracellular and Kinase Domain KIT Mutants

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Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Pathway

Has Part(s)

11 items

Phosphorylated KIT Mutants Bind PI3K

KIT Mutants:PI3K Catalyze Synthesis of PIP3

KIT Mutants Bind GRB2-SOS

P-KIT Mutants:GRB2:SOS Catalyzes Nucleotide Exchange on RAS

KIT Mutants Bind SFKs

JAK2 Binds to P-KIT Mutants

Phosphorylation of JAK2 Downstream of KIT Mutants

Recruitment of STATs by KIT Mutants

Phosphorylation of STATs Downstream of KIT Mutants

Dimerization of STATs Downstream of KIT Mutants

Disassociation and Translocation of STATs to the Nucleus Downstream of KIT Mutants

Part Of

Signaling by KIT in Disease