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Signaling by ERBB2 TMD/JMD Mutants
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9665686).
Statements about
Signaling by ERBB2 TMD/JMD Mutants
Exact Match
https://identifiers.org/reactome:R-H ...
Instance Of
Biological Pathway
Has Part(s)
13 items
Part Of
Phosphorylated Heterodimers of ERBB2 TMD/JMD Mutants Recruit GRB2:SOS1 Through SHC1
Phosphorylated Heterodimers of ERBB2 TMD/JMD Mutants Phosphorylate SHC1
RAS Activation by SOS1 Bound to Phosphorylated Heterodimers of ERBB2 TMD/JMD Mutants and EGFR
ERBB2 TMD/JMD Heterodimers Trans-Autophosphorylate
Phosphorylated ERBB2 TMD/JMD Heterodimers Bind SHC1
Phosphorylated Heterodimers of ERBB2 TMD/JMD Mutants and EGFR Bind GRB2:SOS1
ERBB2 TMD/JMD Mutants Hetrodimerize
Signaling by ERBB2 in Cancer
ERBB2 TMD/JMD Mutants Bind TKIs
ERBB2 TMD/JMD Mutants Bind Trastuzumab
RAS Activation by SOS1 Bound to Phosphorylated Heterodimers of ERBB2 TMD/JMD Mutants
Phosphorylated Heterodimers of ERBB2 TMD/JMD Mutants and EGFR Phosphorylate PLCG1
ERBB2 TMD/JMD Mutants Bind Pertuzumab
Phosphorylated Heterodimers of ERBB2 TMD/JMD Mutants and EGFR Bind PLCG1