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Transcriptional Regulation of Granulopoiesis
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9616222).
Statements about
Transcriptional Regulation of Granulopoiesis
Exact Match
https://identifiers.org/reactome:R-H ...
Instance Of
Biological Pathway
Granulocyte Differentiation
Has Part(s)
27 items
SPI1 (PU.1) Gene Transcription Is Stimulated by RUNX1:CBFB:KMT2A
RUNX1, SPI1 (PU.1), GATA2, TAL1 (SCL), FLI1, and MYB Bind the CEBPA Promoter
LEF1 Binds the Promoter of the CEBPA Gene
CEBPA Gene Transcription Is Enhanced by RUNX1, SPI1 (PU.1), GATA2, TAL1 (SCL), FLI1, MYB, LEF1, and CEBPA
CEBPA mRNA Is Translated to Yield CEBPA Protein
CEBPA Binds CDK2
CEBPA Binds CDK4
CEBPA Binds CDKN1A (P21)
CEBPA Binds the Promoter of the CEBPE Gene
SPI1 (PU.1), PML Isoform 4, and EP300 Bind the Promoter of the CEBPE Gene
All-Trans Retinoic Acid Binds RARA:RXRA at the Promoter of the CEBPE Gene
CEBPE Gene Expression Is Enhanced by CEBPA, SPI1 (PU.1), and Retinoic Acid
CEBPA Binds the Promoter of the GFI1 Gene
GFI1 Gene Expression Is Enhanced by CEBPA
SPI1 (PU.1), CEBPA and DEK Bind the Promoter of the CSF3R (G-CSFR) Gene
CSF3R Gene Expression Is Enhanced by SPI1 (PU.1), CEBPA, and DEK
IL6R Gene Expression Is Enhanced by CEBPA
Phospho-STAT3 Binds the Promoter of the CEBPB Gene
Phospho-CREB1 Binds the Promoter of the CEBPB Gene
CEBPB Gene Transcription Is Enhanced by Phospho-CREB1 and Phospho-STAT3
CEBPB mRNA Is Translated to Yield CEBPB Protein
E2F1 Binds the Promoter of the MYC Gene
CEBPA Binds MYC Gene:E2F1
CEBPB and Phospho-STAT3 Bind the Promoter of the MYC Gene
MYC Gene Expression Is Enhanced by E2F1, STAT3, and CEBPB and Repressed by CEBPA
CEBPA Binds the Promoter of the KLF5 Gene
KLF5 Gene Expression Is Enhanced by CEBPA
Part Of
Developmental Biology
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