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Amino Acids Regulate mTORC1 - Ontify

Amino Acids Regulate mTORC1

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9639288).

Statements about Amino Acids Regulate mTORC1

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Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Pathway

Cellular Response to Amino Acid Starvation

Has Part(s)

12 items

SESN1,2 Binds L-Leucine and Dissociates From GATOR2

CASTOR1 in CASTOR1:CASTOR2 Binds L-Arginine and Dissociates From GATOR2

CASTOR1 Homodimer Binds L-Arginine and Dissociates From GATOR2

BMT2 (SAMTOR) Binds S-Adenosylmethionine and Dissociates From KICSTOR:GATOR1

RRAGC,D Exchanges GTP for GDP

RRAGC,D Hydrolyzes GTP

V-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP Binds SLC38A9:Arginine

RRAGA,B Exchanges GDP for GTP

V-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine Dissociates Yielding V-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine

V-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP Binds mTORC1

MTORC1 Binds RHEB:GTP

RRAGA,B Hydrolyzes GTP

Part Of

Cellular Response to Starvation