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TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9686731).

Statements about TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis

Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Process

Has Part(s)

S3:M:E:encapsidated SARS Coronavirus Genomic RNA: 7a:O-Glycosyl 3a Tetramer:glycosylated-ACE2 [Extracellular Region]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
S1:S2:M:E:encapsidated SARS Coronavirus Genomic RNA: 7a:O-Glycosyl 3a Tetramer [Endocytic Vesicle Lumen]
Object of Statement Has Role
:
Product
Unnamed
: 1

Part Of

Attachment and Entry
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Transmembrane Serine Protease 2
Object of Statement Has Role
:
Modifier
Unnamed
: 1
Angiotensin I Converting Enzyme 2
Object of Statement Has Role
:
Product
Unnamed
: 1
TMPRSS2:TMPRSS2 Inhibitors [Plasma Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
: 1